Royal Air Force Typhoon FGR4s have conducted a mission with French aircraft in a coordinated attack on an hidden munitions depot in Syria used by the Daesh militant organization, per a report from the UK's MoD.
The site, located using intelligence, was thought to be housing weapons and explosive materials, the release indicated, and was situated in mountainous terrain just to the north of the historic site of Palmyra in central Syria.
"Our aircraft used laser-guided Paveway IV weapons to target a series of access tunnels down to the depot... early reports indicate the objective was successfully hit," the MoD said.
There was no evidence of any civilian impact in the attack on Saturday evening and every plane involved returned safely, the defence officials confirmed.
The Typhoon fighters were supported by a Voyager aerial refuelling aircraft.
IS - also known as Daesh - imposed jihadist rule over large swathes of both Syria and Iraq until 2019.
"This strike underscores our UK leadership, and resolve to work closely with our partners, to eliminate any revival of Daesh and their harmful and extremist ideologies in the Middle East," Britain's Defence Chief the Defence Secretary said.
UK warplanes have carried out patrols over Syria to "prevent any efforts to regroup" of Islamic State following its routing at the climactic battle in Baghuz in the year 2019, the authorities noted.
"I must thank all the members of British forces participating in this mission for their skill and their courage," Healey commented. "Including them were thousands of British personnel on duty over the holidays. This action, to eliminate terrorist threats who threaten our security, highlights how our armed forces are always on standby, all year round, protecting the UK within its borders and strong abroad."
During December, the US military carried out what it described as a "massive strike" against IS targets in the country, following an ambush killed two US servicemembers and a civilian linguist in Palmyra.
The UN estimates IS still maintains roughly 5-7 thousand militants in both countries.